YBX1
Information YBX1
- Description
This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]
- Full Name
Y-box binding protein 1
- Source NCBI
ReMap Statistics
- Datasets
- 4
- Biotypes
- 4
- Peaks
- 10,705
- Non-redundant peaks
- 8,438
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000065978
- UniProt
- P67809
- Genevisible
- P67809
- RefSeq
- NM_004559
- Aliases
- BP-8; CBF-A; CSDA2; CSDB; DBPB; EFI-A; MDR-NF1; NSEP-1; NSEP1; YB-1; YB1
Datasets Table for YBX1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| YBX1 | GM12878 | ENCODE | Homo sapiens | ENCSR205SKQ | 3,125 | |||
| YBX1 | Hep-G2 | ENCODE | Homo sapiens | ENCSR799GOY | 4,914 | |||
| YBX1 | K-562 | ENCODE | Homo sapiens | ENCSR107RHZ | 1,696 | |||
| YBX1 | MCF-7 | ENCODE | Homo sapiens | ENCSR864KNH | 970 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |