YAP1

Information YAP1

Description

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]

Full Name

Yes associated protein 1

Source NCBI

ReMap Statistics

Datasets
9
Biotypes
9
Peaks
50,071
Non-redundant peaks
39,024

TF Classification

Super Class
Unknown
Class
Unknown
Familly
Unknown
Sub Familly
Unknown

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000137693
UniProt
P46937
Genevisible
P46937
RefSeq
NM_001130145
Aliases
COB1; YAP; YAP2; YAP65; YKI
All peaks YAP1
Download BED file
Non redundant peaks YAP1
Download BED file
SEQUENCES YAP1
Download FASTA file
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Datasets Table for YAP1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
YAP1 MCF-7 GEO Homo sapiens GSE107013 9,114
YAP1 CCLP1 GEO Homo sapiens GSE62272 91
YAP1 HUCCT1 GEO Homo sapiens GSE68296 167
YAP1 MSTO GEO Homo sapiens GSE68170 1,199
YAP1 H69 GEO Homo sapiens GSE62274 1,175
YAP1 MDA-MB-231 GEO Homo sapiens GSE66081 15,906
YAP1 OVCAR-5 GEO Homo sapiens GSE57236 8,916
YAP1 MCF-10A GEO Homo sapiens GSE97972 12,857
YAP1 WA01 GEO Homo sapiens GSE99202 646
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.