XRCC5
Information XRCC5
- Description
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
- Full Name
X-ray repair cross complementing 5
- Source NCBI
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 221,338
- Non-redundant peaks
- 196,137
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000079246
- UniProt
- P13010
- Genevisible
- P13010
- RefSeq
- NM_021141
- Aliases
- KARP-1; KARP1; KU80; KUB2; Ku86; NFIV
Datasets Table for XRCC5
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| XRCC5 | Hep-G2 | ENCODE | Homo sapiens | ENCSR031URL | 172,890 | |||
| XRCC5 | K-562 | ENCODE | Homo sapiens | ENCSR506KWJ | 48,448 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |