USF1
Information USF1
- Description
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21. [provided by RefSeq, Feb 2013]
- Full Name
upstream transcription factor 1
- Source NCBI
ReMap Statistics
- Datasets
- 11
- Biotypes
- 8
- Peaks
- 295,602
- Non-redundant peaks
- 133,104
TF Classification
- Super Class
- Basic domains
- Class
- Basic helix-loop-helix factors (bHLH)
- Familly
- bHLH-ZIP factors
- Sub Familly
- USF factors
Source TFClass
External IDs
- JASPAR
- MA0093
- Ensembl
- ENSG00000158773
- UniProt
- P22415
- Genevisible
- P22415
- RefSeq
- NM_001276373
- Aliases
- FCHL; FCHL1; HYPLIP1; MLTF; MLTFI; UEF; bHLHb11
Datasets Table for USF1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| USF1 | GM12878 | ENCODE | Homo sapiens | ENCSR000BGI | 9,331 | |||
| USF1 | Ishikawa | ENCODE | Homo sapiens | ENCSR000BSX | 32,021 | |||
| USF1 | A-549 | ENCODE | Homo sapiens | ENCSR000BHX | 10,399 | |||
| USF1 | A-549 | ENCODE | Homo sapiens | ENCSR000BJB | 14,479 | |||
| USF1 | A-549 | ENCODE | Homo sapiens | ENCSR000BPV | 17,749 | |||
| USF1 | Hep-G2 | ENCODE | Homo sapiens | ENCSR000BGM | 28,325 | |||
| USF1 | K-562 | ENCODE | Homo sapiens | ENCSR000BKT | 43,123 | |||
| USF1 | SK-N-SH | ENCODE | Homo sapiens | ENCSR000BMF | 55,214 | |||
| USF1 | SK-N-SH | ENCODE | Homo sapiens | ENCSR000BTZ | 12,911 | |||
| USF1 | WA01 | ENCODE | Homo sapiens | ENCSR000BIU | 59,924 | |||
| USF1 | HCT-116 | ENCODE | Homo sapiens | ENCSR000BVK | 12,126 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |