TRIM25
Information TRIM25
- Description
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq, Jul 2008]
- Full Name
tripartite motif containing 25
- Source NCBI
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 47,782
- Non-redundant peaks
- 47,782
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000121060
- UniProt
- Q14258
- Genevisible
- Q14258
- RefSeq
- NM_005082
- Aliases
- EFP; RNF147; Z147; ZNF147
Datasets Table for TRIM25
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| TRIM25 | BT-549 | GEO | Homo sapiens | GSE79588 | 31,403 | |||
| TRIM25 | MDA-MB-231 | GEO | Homo sapiens | GSE79588 | 16,379 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |