TARDBP
Information TARDBP
- Description
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
- Full Name
TAR DNA binding protein
- Source NCBI
ReMap Statistics
- Datasets
- 8
- Biotypes
- 5
- Peaks
- 178,480
- Non-redundant peaks
- 125,975
TF Classification
- Super Class
- Unknown
- Class
- Unknown
- Familly
- Unknown
- Sub Familly
- Unknown
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000120948
- UniProt
- Q13148
- Genevisible
- Q13148
- RefSeq
- NM_007375
- Aliases
- ALS10; TDP-43
Datasets Table for TARDBP
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| TARDBP | GM12878 | ENCODE | Homo sapiens | ENCSR016UEH | 8,314 | |||
| TARDBP | GM12878 | ENCODE | Homo sapiens | ENCSR412QBS | 71,929 | |||
| TARDBP | HEK293T | ENCODE | Homo sapiens | ENCSR753GIA | 1,223 | |||
| TARDBP | Hep-G2 | ENCODE | Homo sapiens | ENCSR145CXH | 23,983 | |||
| TARDBP | K-562 | ENCODE | Homo sapiens | ENCSR033VAZ | 9,121 | |||
| TARDBP | K-562 | ENCODE | Homo sapiens | ENCSR353HEP | 13,405 | |||
| TARDBP | K-562 | ENCODE | Homo sapiens | ENCSR429XTR | 33,355 | |||
| TARDBP | MCF-7 | ENCODE | Homo sapiens | ENCSR801SWX | 17,150 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |