SREBF2

Information SREBF2

Description

This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Full Name

sterol regulatory element binding transcription factor 2

Source NCBI

ReMap Statistics

Datasets
4
Biotypes
4
Peaks
24,320
Non-redundant peaks
23,472

TF Classification

Super Class
Basic domains
Class
Basic helix-loop-helix factors (bHLH)
Familly
bHLH-ZIP factors
Sub Familly
SREBP factors

Source TFClass

External IDs

JASPAR
MA0828
Ensembl
ENSG00000198911
UniProt
Q12772
Genevisible
Q12772
RefSeq
NM_004599
Aliases
SREBP-2; SREBP2; bHLHd2
All peaks SREBF2
Download BED file
Non redundant peaks SREBF2
Download BED file
SEQUENCES SREBF2
Download FASTA file
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Datasets Table for SREBF2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SREBF2 GM12878 ENCODE Homo sapiens ENCSR000DYT 656
SREBF2 A-549 ENCODE Homo sapiens ENCSR638QYO 417
SREBF2 Hep-G2 ENCODE Homo sapiens ENCSR000EZO 275
SREBF2 HeLa-S3 ENCODE Homo sapiens ENCSR611WZO 22,972
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.