SRC

Information SRC

Description

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Full Name

SRC proto-oncogene, non-receptor tyrosine kinase

Source NCBI

ReMap Statistics

Datasets
4
Biotypes
1
Peaks
9,149
Non-redundant peaks
5,935

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000197122
UniProt
P12931
Genevisible
P12931
RefSeq
NM_005417
Aliases
ASV; SRC1; THC6; c-SRC; c-src; p60-Src
All peaks SRC
Download BED file
Non redundant peaks SRC
Download BED file
SEQUENCES SRC
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for SRC

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SRC MDA-MB-231 GEO Homo sapiens GSE95121 288
SRC MDA-MB-231 45min GEO Homo sapiens GSE95121 2,493
SRC MDA-MB-231 LQ GEO Homo sapiens GSE95121 2,778
SRC MDA-MB-231 LQ_45min GEO Homo sapiens GSE95121 3,590
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.