SOX6
Information SOX6
- Description
This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
- Full Name
SRY-box transcription factor 6
- Source NCBI
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 48,168
- Non-redundant peaks
- 48,151
TF Classification
- Super Class
- Other all-alpha-helical DNA-binding domains
- Class
- High-mobility group (HMG) domain factors
- Familly
- SOX-related factors
- Sub Familly
- Group D
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000110693
- UniProt
- P35712
- Genevisible
- P35712
- RefSeq
- NM_001145811
- Aliases
Datasets Table for SOX6
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SOX6 | Hep-G2 | ENCODE | Homo sapiens | ENCSR543BVU | 2,005 | |||
| SOX6 | K-562 | ENCODE | Homo sapiens | ENCSR788RSW | 46,163 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |