SOX4
Information SOX4
- Description
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008]
- Full Name
SRY-box transcription factor 4
- Source NCBI
ReMap Statistics
- Datasets
- 9
- Biotypes
- 4
- Peaks
- 67,533
- Non-redundant peaks
- 49,278
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- JASPAR
- MA0867
- Ensembl
- ENSG00000124766
- UniProt
- Q06945
- Genevisible
- Q06945
- RefSeq
- NM_003107
- Aliases
- EVI16
Datasets Table for SOX4
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SOX4 | HCC1954 | GEO | Homo sapiens | GSE104760 | 7,814 | |||
| SOX4 | HCC1954 | TGFb | GEO | Homo sapiens | GSE104760 | 3,565 | ||
| SOX4 | MDA-MB-231 | GEO | Homo sapiens | GSE104760 | 19,732 | |||
| SOX4 | MDA-MB-231 | TGFb | GEO | Homo sapiens | GSE104760 | 15,057 | ||
| SOX4 | HMLE | GEO | Homo sapiens | GSE104760 | 180 | |||
| SOX4 | HMLE | Doxycicline | GEO | Homo sapiens | GSE104760 | 251 | ||
| SOX4 | HMLE | Doxycicline_TGFb | GEO | Homo sapiens | GSE104760 | 682 | ||
| SOX4 | HMLE | TGFb | GEO | Homo sapiens | GSE104760 | 570 | ||
| SOX4 | MRC-5 | 1DPT | GEO | Homo sapiens | GSE75910 | 19,682 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |