SOX2
Information SOX2
- Description
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
- Full Name
SRY-box transcription factor 2
- Source NCBI
ReMap Statistics
- Datasets
- 20
- Biotypes
- 13
- Peaks
- 377,627
- Non-redundant peaks
- 288,800
TF Classification
- Super Class
- Other all-alpha-helical DNA-binding domains
- Class
- High-mobility group (HMG) domain factors
- Familly
- SOX-related factors
- Sub Familly
- Group B
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000181449
- UniProt
- P48431
- Genevisible
- P48431
- RefSeq
- NM_003106
- Aliases
- ANOP3; MCOPS3
Datasets Table for SOX2
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
---|---|---|---|---|---|---|---|---|
SOX2 | BJ | INDUCED | GEO | Homo sapiens | GSE36570 | 121,462 | ||
SOX2 | glioma | stem | GEO | Homo sapiens | GSE67282 | 3,859 | ||
SOX2 | hESC | GEO | Homo sapiens | GSE18292 | 18,963 | |||
SOX2 | hESC | GEO | Homo sapiens | GSE69479 | 2,352 | |||
SOX2 | HNSC | GEO | Homo sapiens | GSE69479 | 74,636 | |||
SOX2 | KYSE70 | GEO | Homo sapiens | GSE46837 | 6,840 | |||
SOX2 | RENVM | GEO | Homo sapiens | GSE49404 | 38,149 | |||
SOX2 | RENVM | SHSOX2 | GEO | Homo sapiens | GSE49404 | 4,497 | ||
SOX2 | TT | GEO | Homo sapiens | GSE46837 | 10,181 | |||
SOX2 | H9 | GEO | Homo sapiens | GSE46837 | 3,216 | |||
SOX2 | hiPSC | GEO | Homo sapiens | GSE56567 | 64,223 | |||
SOX2 | hiPSC | GEO | Homo sapiens | GSE67282 | 6,645 | |||
SOX2 | hiPSC | INHI | GEO | Homo sapiens | GSE67282 | 3,238 | ||
SOX2 | hiPSC | KDP53 | GEO | Homo sapiens | GSE67282 | 5,025 | ||
SOX2 | hiPSC | KDP53_INHI | GEO | Homo sapiens | GSE67282 | 6,198 | ||
SOX2 | hiPSC | 3s2 | GEO | Homo sapiens | GSE81899 | 879 | ||
SOX2 | OSK | GEO | Homo sapiens | GSE81899 | 1,237 | |||
SOX2 | OSKM | GEO | Homo sapiens | GSE81899 | 5,507 | |||
SOX2 | OSvK | GEO | Homo sapiens | GSE81899 | 263 | |||
SOX2 | OSvKM | GEO | Homo sapiens | GSE81899 | 257 | |||
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |