SOX10
Information SOX10
- Description
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, Jul 2008]
- Full Name
SRY-box transcription factor 10
- Source NCBI
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 4,198
- Non-redundant peaks
- 4,198
TF Classification
- Super Class
- Other all-alpha-helical DNA-binding domains
- Class
- High-mobility group (HMG) domain factors
- Familly
- SOX-related factors
- Sub Familly
- Group E
Source TFClass
External IDs
- JASPAR
- MA0442
- Ensembl
- ENSG00000100146
- UniProt
- P56693
- Genevisible
- P56693
- RefSeq
- NM_006941
- Aliases
- DOM; PCWH; WS2E; WS4; WS4C