SMARCE1
Information SMARCE1
- Description
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq, Jul 2008]
- Full Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
- Source NCBI
ReMap Statistics
- Datasets
- 4
- Biotypes
- 4
- Peaks
- 107,814
- Non-redundant peaks
- 101,964
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000073584
- UniProt
- Q969G3
- Genevisible
- Q969G3
- RefSeq
- NM_003079
- Aliases
- BAF57; CSS5
Datasets Table for SMARCE1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SMARCE1 | Hep-G2 | ENCODE | Homo sapiens | ENCSR968QDP | 608 | |||
| SMARCE1 | K-562 | ENCODE | Homo sapiens | ENCSR157TCS | 63,058 | |||
| SMARCE1 | MCF-7 | ENCODE | Homo sapiens | ENCSR431TLD | 30,084 | |||
| SMARCE1 | HMLE-Twist-ER | 125nM_4OHT | GEO | Homo sapiens | GSE96933 | 14,064 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |