PPARG
Information PPARG
- Description
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
- Full Name
peroxisome proliferator activated receptor gamma
- Source NCBI
ReMap Statistics
- Datasets
- 12
- Biotypes
- 8
- Peaks
- 196,982
- Non-redundant peaks
- 149,431
TF Classification
- Super Class
- Zinc-coordinating DNA-binding domains
- Class
- Nuclear receptors with C4 zinc fingers
- Familly
- Thyroid hormone receptor-related factors (NR1)
- Sub Familly
- PPAR (NR1C)
Source TFClass
External IDs
- JASPAR
- MA0066
- Ensembl
- ENSG00000132170
- UniProt
- P37231
- Genevisible
- P37231
- RefSeq
- NM_001330615
- Aliases
- CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma
Datasets Table for PPARG
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| PPARG | macrophage | ENA | Homo sapiens | ERP008801 | 621 | |||
| PPARG | Hep-G2 | ENCODE | Homo sapiens | ENCSR130VQL | 79,137 | |||
| PPARG | WPMY-1 | ENA | Homo sapiens | ERP000333 | 567 | |||
| PPARG | ASC | GEO | Homo sapiens | GSE21366 | 24,901 | |||
| PPARG | HT29 | ROSIG_2H | GEO | Homo sapiens | GSE77039 | 26,553 | ||
| PPARG | HT29 | ROSIG_48H | GEO | Homo sapiens | GSE77039 | 16,974 | ||
| PPARG | SGBS | GEO | Homo sapiens | GSE41629 | 11,945 | |||
| PPARG | HUVEC-C | DMSO_HYPO | GEO | Homo sapiens | GSE50144 | 25,665 | ||
| PPARG | HUVEC-C | DMSO_NORMO | GEO | Homo sapiens | GSE50144 | 536 | ||
| PPARG | HUVEC-C | PPARG_HYPO | GEO | Homo sapiens | GSE50144 | 8,855 | ||
| PPARG | HUVEC-C | PPARG_NORMO | GEO | Homo sapiens | GSE50144 | 189 | ||
| PPARG | THP-1 | DIFF | GEO | Homo sapiens | GSE25426 | 1,039 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |