PGR
Information PGR
- Description
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]
- Full Name
progesterone receptor
- Source NCBI
ReMap Statistics
- Datasets
- 27
- Biotypes
- 9
- Peaks
- 767,916
- Non-redundant peaks
- 286,352
TF Classification
- Super Class
- Zinc-coordinating DNA-binding domains
- Class
- Nuclear receptors with C4 zinc fingers
- Familly
- Steroid hormone receptors (NR3)
- Sub Familly
- GR-like receptors (NR3C)
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000082175
- UniProt
- P06401
- Genevisible
- P06401
- RefSeq
- NM_000926
- Aliases
- NR3C3; PR
Datasets Table for PGR
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| PGR | breast | tumor_Male_26 | GEO | Homo sapiens | GSE104399 | 54,695 | ||
| PGR | breast | tumor_Male_28 | GEO | Homo sapiens | GSE104399 | 25,702 | ||
| PGR | breast | tumor_Male_30 | GEO | Homo sapiens | GSE104399 | 22,479 | ||
| PGR | AB32 | GEO | Homo sapiens | GSE31129 | 49,447 | |||
| PGR | breast | tumor-xenograft_1_E2_P4 | GEO | Homo sapiens | GSE93108 | 151 | ||
| PGR | A | hESC | GEO | Homo sapiens | GSE62475 | 3,996 | ||
| PGR | B | hESC | GEO | Homo sapiens | GSE62475 | 10,530 | ||
| PGR | hESC | GEO | Homo sapiens | GSE69539 | 8,691 | |||
| PGR | Leiomyoma | RU486 | GEO | Homo sapiens | GSE40724 | 26,649 | ||
| PGR | HUVEC-C | GEO | Homo sapiens | GSE43786 | 10 | |||
| PGR | HUVEC-C | PR | GEO | Homo sapiens | GSE43786 | 29 | ||
| PGR | HUVEC-C | PR_PROGESTERON | GEO | Homo sapiens | GSE43786 | 4,665 | ||
| PGR | MCF-7 | PROG | GEO | Homo sapiens | GSE68355 | 73,610 | ||
| PGR | MCF-7 | R5020 | GEO | Homo sapiens | GSE68355 | 52,356 | ||
| PGR | T-47D | GEO | Homo sapiens | GSE31129 | 28,744 | |||
| PGR | T-47D | GEO | Homo sapiens | GSE40724 | 97,265 | |||
| PGR | T-47D | PROG | GEO | Homo sapiens | GSE68355 | 73,273 | ||
| PGR | T-47D | R5020 | GEO | Homo sapiens | GSE68355 | 64,691 | ||
| PGR | T-47D | E2 | GEO | Homo sapiens | GSE68356 | 122 | ||
| PGR | T-47D | E2PG | GEO | Homo sapiens | GSE68356 | 12,514 | ||
| PGR | T-47D | PG | GEO | Homo sapiens | GSE68356 | 12,293 | ||
| PGR | T-47D-A | E2_R5020 | GEO | Homo sapiens | GSE80358 | 14,550 | ||
| PGR | T-47D-A | R5020 | GEO | Homo sapiens | GSE80358 | 6,602 | ||
| PGR | T-47D | CR3flp_P4 | GEO | Homo sapiens | GSE99479 | 112,429 | ||
| PGR | T-47D | CR3flp_veh | GEO | Homo sapiens | GSE99479 | 5,899 | ||
| PGR | T-47D-B | E2_R5020 | GEO | Homo sapiens | GSE80358 | 3,164 | ||
| PGR | T-47D-B | R5020 | GEO | Homo sapiens | GSE80358 | 3,360 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |