NFE2L2
Information NFE2L2
- Description
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015]
- Full Name
nuclear factor, erythroid 2 like 2
- Source NCBI
ReMap Statistics
- Datasets
- 10
- Biotypes
- 8
- Peaks
- 186,524
- Non-redundant peaks
- 111,325
TF Classification
- Super Class
- Basic domains
- Class
- Basic leucine zipper factors (bZIP)
- Familly
- Jun-related factors
- Sub Familly
- NF-E2-like factors
Source TFClass
External IDs
- JASPAR
- MA0150
- Ensembl
- ENSG00000116044
- UniProt
- Q16236
- Genevisible
- Q16236
- RefSeq
- NM_001145412
- Aliases
- HEBP1; IMDDHH; NRF2
Datasets Table for NFE2L2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| NFE2L2 | A-549 | ENCODE | Homo sapiens | ENCSR584GHV | 10,665 | |||
| NFE2L2 | Hep-G2 | ENCODE | Homo sapiens | ENCSR488EES | 18,033 | |||
| NFE2L2 | IMR-90 | ENCODE | Homo sapiens | ENCSR197WGI | 32,792 | |||
| NFE2L2 | K-562 | ENCODE | Homo sapiens | ENCSR485GKE | 55,982 | |||
| NFE2L2 | HeLa-S3 | ENCODE | Homo sapiens | ENCSR707IUN | 28,149 | |||
| NFE2L2 | BEAS-2B | GEO | Homo sapiens | GSE75812 | 204 | |||
| NFE2L2 | A-549 | GEO | Homo sapiens | GSE113497 | 21,751 | |||
| NFE2L2 | A-375 | A771726 | GEO | Homo sapiens | GSE57431 | 5,654 | ||
| NFE2L2 | A-375 | DMSO | GEO | Homo sapiens | GSE57431 | 11,031 | ||
| NFE2L2 | HAEC | oxpapc_4h | GEO | Homo sapiens | GSE89970 | 2,263 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |