MYB
Information MYB
- Description
This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
- Full Name
MYB proto-oncogene, transcription factor
- Source NCBI
ReMap Statistics
- Datasets
- 14
- Biotypes
- 10
- Peaks
- 366,411
- Non-redundant peaks
- 163,201
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Tryptophan cluster factors
- Familly
- Myb/SANT domain factors
- Sub Familly
- Myb-like factors
Source TFClass
External IDs
- JASPAR
- MA0100
- Ensembl
- ENSG00000118513
- UniProt
- P10242
- Genevisible
- P10242
- RefSeq
- NM_001130172
- Aliases
- Cmyb; c-myb; c-myb_CDS; efg
Datasets Table for MYB
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MYB | GM12878 | ENCODE | Homo sapiens | ENCSR819ATC | 11,496 | |||
| MYB | CD4 | TH1 | GEO | Homo sapiens | GSE72266 | 37,257 | ||
| MYB | CD4 | TH2 | GEO | Homo sapiens | GSE72266 | 11,474 | ||
| MYB | Jurkat | GEO | Homo sapiens | GSE59657 | 63,691 | |||
| MYB | Loucy | GEO | Homo sapiens | GSE94000 | 36,385 | |||
| MYB | DU528 | GEO | Homo sapiens | GSE94000 | 31,386 | |||
| MYB | MOLT-3 | GEO | Homo sapiens | GSE59657 | 48,404 | |||
| MYB | MV4-11 | GEO | Homo sapiens | GSE94240 | 243 | |||
| MYB | MV4-11 | TG3 | GEO | Homo sapiens | GSE94240 | 256 | ||
| MYB | PF-382 | GEO | Homo sapiens | GSE94000 | 26,208 | |||
| MYB | THP-1 | GEO | Homo sapiens | GSE90769 | 58,310 | |||
| MYB | THP-1 | OG86 | GEO | Homo sapiens | GSE90769 | 39,366 | ||
| MYB | U-937 | ATRA-treated_MYB | GEO | Homo sapiens | GSE98006 | 447 | ||
| MYB | U-937 | vehicle-treated_MYB | GEO | Homo sapiens | GSE98006 | 1,488 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |