MRTFA

Information MRTFA

Description

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Full Name

myocardin related transcription factor A

Source NCBI

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
10,866
Non-redundant peaks
10,866

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000196588
UniProt
Q969V6
Genevisible
Q969V6
RefSeq
NM_001282660
Aliases
BSAC; KIAA1438; MAL; MKL; MRTF-A
All peaks MRTFA
Download BED file
Non redundant peaks MRTFA
Download BED file
SEQUENCES MRTFA
Download FASTA file
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Datasets Table for MRTFA

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MRTFA A-673-clone-Asp114 GEO Homo sapiens GSE92738 10,866
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.