MEF2C
Information MEF2C
- Description
This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
- Full Name
myocyte enhancer factor 2C
- Source NCBI
ReMap Statistics
- Datasets
- 4
- Biotypes
- 3
- Peaks
- 111,645
- Non-redundant peaks
- 105,670
TF Classification
- Super Class
- alpha-Helices exposed by beta-structures
- Class
- MADS box factors
- Familly
- Regulators of differentiation
- Sub Familly
- MEF-2
Source TFClass
External IDs
- JASPAR
- MA0497
- Ensembl
- ENSG00000081189
- UniProt
- Q06413
- Genevisible
- Q06413
- RefSeq
- NM_001131005
- Aliases
- C5DELq14.3; DEL5q14.3
Datasets Table for MEF2C
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MEF2C | GM12878 | ENCODE | Homo sapiens | ENCSR000BNG | 10,379 | |||
| MEF2C | HUVEC-C | GEO | Homo sapiens | GSE32644 | 277 | |||
| MEF2C | HUVEC-C | STATIN | GEO | Homo sapiens | GSE32644 | 242 | ||
| MEF2C | MOLM-13 | GEO | Homo sapiens | GSE109492 | 100,747 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |