MEF2A
Information MEF2A
- Description
The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
- Full Name
myocyte enhancer factor 2A
- Source NCBI
ReMap Statistics
- Datasets
- 3
- Biotypes
- 3
- Peaks
- 50,670
- Non-redundant peaks
- 47,336
TF Classification
- Super Class
- alpha-Helices exposed by beta-structures
- Class
- MADS box factors
- Familly
- Regulators of differentiation
- Sub Familly
- MEF-2
Source TFClass
External IDs
- JASPAR
- MA0052
- Ensembl
- ENSG00000068305
- UniProt
- Q02078
- Genevisible
- Q02078
- RefSeq
- NM_001130926
- Aliases
- ADCAD1; RSRFC4; RSRFC9; mef2
Datasets Table for MEF2A
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MEF2A | GM12878 | ENCODE | Homo sapiens | ENCSR000BKB | 34,610 | |||
| MEF2A | K-562 | ENCODE | Homo sapiens | ENCSR000BNV | 4,345 | |||
| MEF2A | SK-N-SH | ENCODE | Homo sapiens | ENCSR000BVC | 11,715 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |