MAFF
Information MAFF
- Description
The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
- Full Name
MAF bZIP transcription factor F
- Source NCBI
ReMap Statistics
- Datasets
- 4
- Biotypes
- 4
- Peaks
- 187,218
- Non-redundant peaks
- 123,831
TF Classification
- Super Class
- Basic domains
- Class
- Basic leucine zipper factors (bZIP)
- Familly
- Maf-related factors
- Sub Familly
- Small Maf factors
Source TFClass
External IDs
- JASPAR
- MA0495
- Ensembl
- ENSG00000185022
- UniProt
- Q9ULX9
- Genevisible
- Q9ULX9
- RefSeq
- NM_001161572
- Aliases
- U-MAF; hMafF
Datasets Table for MAFF
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MAFF | GM12878 | ENCODE | Homo sapiens | ENCSR237YZZ | 6,053 | |||
| MAFF | Hep-G2 | ENCODE | Homo sapiens | ENCSR000EEC | 82,791 | |||
| MAFF | K-562 | ENCODE | Homo sapiens | ENCSR000EGI | 29,370 | |||
| MAFF | HeLa-S3 | ENCODE | Homo sapiens | ENCSR140DSL | 69,004 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |