KLF1
Information KLF1
- Description
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009]
- Full Name
Kruppel like factor 1
- Source NCBI
ReMap Statistics
- Datasets
- 6
- Biotypes
- 4
- Peaks
- 137,964
- Non-redundant peaks
- 87,086
TF Classification
- Super Class
- Zinc-coordinating DNA-binding domains
- Class
- C2H2 zinc finger factors
- Familly
- Three-zinc finger Krüppel-related factors
- Sub Familly
- Krüppel-like factors
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000105610
- UniProt
- Q13351
- Genevisible
- Q13351
- RefSeq
- NM_006563
- Aliases
- EKLF; EKLF/KLF1
Datasets Table for KLF1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| KLF1 | HEK293 | ENCODE | Homo sapiens | ENCSR859BMR | 48,308 | |||
| KLF1 | K-562 | ENCODE | Homo sapiens | ENCSR550HCT | 9,963 | |||
| KLF1 | erythroid | R3R4 | GEO | Homo sapiens | GSE43625 | 34,995 | ||
| KLF1 | HEK293 | GEO | Homo sapiens | GSE76494 | 25,216 | |||
| KLF1 | HUDEP-2 | S2 | GEO | Homo sapiens | GSE97671 | 8,490 | ||
| KLF1 | HUDEP-2 | S4 | GEO | Homo sapiens | GSE97671 | 10,992 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |