JARID2
Information JARID2
- Description
This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]
- Full Name
jumonji and AT-rich interaction domain containing 2
- Source NCBI
ReMap Statistics
- Datasets
- 10
- Biotypes
- 8
- Peaks
- 113,328
- Non-redundant peaks
- 62,681
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- ARID domain factors
- Familly
- ARID-related factors
- Sub Familly
- JARID2
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000008083
- UniProt
- Q92833
- Genevisible
- Q92833
- RefSeq
- NM_001267040
- Aliases
- JMJ
Datasets Table for JARID2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| JARID2 | AMIPS6 | GEO | Homo sapiens | GSE48516 | 12,580 | |||
| JARID2 | AMIPS8 | GEO | Homo sapiens | GSE48516 | 3,898 | |||
| JARID2 | EDOMIPS2 | GEO | Homo sapiens | GSE48516 | 5,289 | |||
| JARID2 | UTEIPS11 | GEO | Homo sapiens | GSE48516 | 5,849 | |||
| JARID2 | UTEIPS4 | GEO | Homo sapiens | GSE48516 | 3,467 | |||
| JARID2 | UTEIPS6 | GEO | Homo sapiens | GSE48516 | 14,009 | |||
| JARID2 | UTEIPS7 | GEO | Homo sapiens | GSE48516 | 6,904 | |||
| JARID2 | MRC-5 | IPS25_CTR | GEO | Homo sapiens | GSE48515 | 24,538 | ||
| JARID2 | MRC-5 | IPS25_MEG3 | GEO | Homo sapiens | GSE48515 | 33,181 | ||
| JARID2 | MRC-5 | IPS25 | GEO | Homo sapiens | GSE48516 | 3,613 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |