GFI1B
Information GFI1B
- Description
This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
- Full Name
growth factor independent 1B transcriptional repressor
- Source NCBI
ReMap Statistics
- Datasets
- 3
- Biotypes
- 3
- Peaks
- 81,486
- Non-redundant peaks
- 77,361
TF Classification
- Super Class
- Zinc-coordinating DNA-binding domains
- Class
- C2H2 zinc finger factors
- Familly
- More than 3 adjacent zinc finger factors
- Sub Familly
- GFI1 factors
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000165702
- UniProt
- Q5VTD9
- Genevisible
- Q5VTD9
- RefSeq
- NM_001135031
- Aliases
- BDPLT17; ZNF163B
Datasets Table for GFI1B
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| GFI1B | HEK293 | ENCODE | Homo sapiens | ENCSR445PDR | 8,700 | |||
| GFI1B | K-562 | ENCODE | Homo sapiens | ENCSR509GDT | 69,196 | |||
| GFI1B | CD34 | GEO | Homo sapiens | GSE52924 | 3,590 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |