GATA4

Information GATA4

Description

This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Full Name

GATA binding protein 4

Source NCBI

ReMap Statistics

Datasets
14
Biotypes
8
Peaks
312,452
Non-redundant peaks
213,465

TF Classification

Super Class
Zinc-coordinating DNA-binding domains
Class
Other C4 zinc finger-type factors
Familly
GATA-type zinc fingers
Sub Familly
Two zinc-finger GATA factors

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000285109
UniProt
P43694
Genevisible
P43694
RefSeq
NM_001308093
Aliases
ASD2; TACHD; TOF; VSD1
All peaks GATA4
Download BED file
Non redundant peaks GATA4
Download BED file
SEQUENCES GATA4
Download FASTA file
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Datasets Table for GATA4

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
GATA4 Hep-G2 ENCODE Homo sapiens ENCSR590CNM 17,508
GATA4 AGS GEO Homo sapiens GSE51705 92,924
GATA4 KATOIII GEO Homo sapiens GSE51705 2,713
GATA4 BJ1-hTERT GEO Homo sapiens GSE92491 72,424
GATA4 BJ1-hTERT FOXA2_GATA4_Coexp GEO Homo sapiens GSE92491 49,638
GATA4 A-549 GEO Homo sapiens GSE85002 9,869
GATA4 YCC-3 GEO Homo sapiens GSE51705 6,962
GATA4 cardiomyocyte GEO Homo sapiens GSE85628 4,973
GATA4 cardiomyocyte 1 GEO Homo sapiens GSE85628 5,259
GATA4 cardiomyocyte 5 GEO Homo sapiens GSE85628 11,759
GATA4 cardiomyocyte 7 GEO Homo sapiens GSE85628 9,981
GATA4 G296S GEO Homo sapiens GSE85628 11,034
GATA4 G296S 2 GEO Homo sapiens GSE85628 11,032
GATA4 G296S 4 GEO Homo sapiens GSE85628 6,376
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

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The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.