FOS
Information FOS
- Description
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]
- Full Name
Fos proto-oncogene, AP-1 transcription factor subunit
- Source NCBI
ReMap Statistics
- Datasets
- 20
- Biotypes
- 13
- Peaks
- 891,093
- Non-redundant peaks
- 255,774
TF Classification
- Super Class
- Basic domains
- Class
- Basic leucine zipper factors (bZIP)
- Familly
- Fos-related factors
- Sub Familly
- Fos factors
Source TFClass
External IDs
- JASPAR
- MA1141
- Ensembl
- ENSG00000170345
- UniProt
- P01100
- Genevisible
- P01100
- RefSeq
- NM_005252
- Aliases
- AP-1; C-FOS; p55
Datasets Table for FOS
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| FOS | endothelial | umbilical-vein | ENCODE | Homo sapiens | ENCSR000EVU | 60,061 | ||
| FOS | GM12878 | ENCODE | Homo sapiens | ENCSR000EYZ | 1,970 | |||
| FOS | Hep-G2 | ENCODE | Homo sapiens | ENCSR177HDZ | 25,964 | |||
| FOS | IMR-90 | ENCODE | Homo sapiens | ENCSR124AIG | 59,276 | |||
| FOS | K-562 | ENCODE | Homo sapiens | ENCSR000DKB | 20,312 | |||
| FOS | K-562 | ENCODE | Homo sapiens | ENCSR000FAI | 14,761 | |||
| FOS | MCF-10A | ENCODE | Homo sapiens | ENCSR000DON | 75,894 | |||
| FOS | MCF-10A | ENCODE | Homo sapiens | ENCSR000DOO | 83,604 | |||
| FOS | MCF-10A | ENCODE | Homo sapiens | ENCSR000DOP | 93,388 | |||
| FOS | MCF-10A | ENCODE | Homo sapiens | ENCSR000DOT | 82,161 | |||
| FOS | MCF-7 | ENCODE | Homo sapiens | ENCSR569XNP | 67,023 | |||
| FOS | THP-1 | eGFP-Pam3csk-0h | GEO | Homo sapiens | GSE103477 | 193 | ||
| FOS | THP-1 | eGFP-Pam3csk-4h | GEO | Homo sapiens | GSE103477 | 6,061 | ||
| FOS | HeLa-S3 | ENCODE | Homo sapiens | ENCSR000EZE | 32,273 | |||
| FOS | MCF10A-Er-Src | EtOH | GEO | Homo sapiens | GSE115597 | 104,017 | ||
| FOS | MCF10A-Er-Src | TAM | GEO | Homo sapiens | GSE115597 | 138,820 | ||
| FOS | MV4-11 | GEO | Homo sapiens | GSE64862 | 7,883 | |||
| FOS | MV4-11 | SHFLT3 | GEO | Homo sapiens | GSE64862 | 4,146 | ||
| FOS | MG-63-3 | GEO | Homo sapiens | GSE74230 | 4,297 | |||
| FOS | MNNG-HOS | GEO | Homo sapiens | GSE74230 | 8,989 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |