ETV6
Information ETV6
- Description
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008]
- Full Name
ETS variant 6
- Source NCBI
ReMap Statistics
- Datasets
- 6
- Biotypes
- 3
- Peaks
- 81,276
- Non-redundant peaks
- 54,941
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Tryptophan cluster factors
- Familly
- Ets-related factors
- Sub Familly
- ETV6-like factors
Source TFClass
External IDs
- JASPAR
- MA0645
- Ensembl
- ENSG00000139083
- UniProt
- P41212
- Genevisible
- P41212
- RefSeq
- NM_001987
- Aliases
- TEL; TEL/ABL; THC5
Datasets Table for ETV6
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| ETV6 | GM12878 | ENCODE | Homo sapiens | ENCSR597VGC | 6,117 | |||
| ETV6 | GM12878 | ENCODE | Homo sapiens | ENCSR626VUC | 26,696 | |||
| ETV6 | K-562 | ENCODE | Homo sapiens | ENCSR000FCE | 4,569 | |||
| ETV6 | K-562 | ENCODE | Homo sapiens | ENCSR124BJR | 6,720 | |||
| ETV6 | Reh | pCCL-ETV6-HA | GEO | Homo sapiens | GSE102785 | 7,329 | ||
| ETV6 | GM12878 | GEO | Homo sapiens | GSE97661 | 29,845 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |