EPAS1
Information EPAS1
- Description
This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]
- Full Name
endothelial PAS domain protein 1
- Source NCBI
ReMap Statistics
- Datasets
- 5
- Biotypes
- 4
- Peaks
- 2,729
- Non-redundant peaks
- 2,484
TF Classification
- Super Class
- Basic domains
- Class
- Basic helix-loop-helix factors (bHLH)
- Familly
- PAS domain factors
- Sub Familly
- Ahr-like factors
Source TFClass
External IDs
- JASPAR
- MA0043
- Ensembl
- ENSG00000116016
- UniProt
- Q99814
- Genevisible
- Q99814
- RefSeq
- NM_001430
- Aliases
- ECYT4; HIF2A; HLF; MOP2; PASD2; bHLHe73
Datasets Table for EPAS1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| EPAS1 | macrophage | HYPO_IL | GEO | Homo sapiens | GSE43109 | 1,145 | ||
| EPAS1 | macrophage | NORMO_IL | GEO | Homo sapiens | GSE43109 | 325 | ||
| EPAS1 | 786-O | GEO | Homo sapiens | GSE34871 | 1,150 | |||
| EPAS1 | HUVEC-C | GEO | Homo sapiens | GSE89836 | 109 | |||
| EPAS1 | ccRCC | GEO | Homo sapiens | GSE86092 | 3,315 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |