EOMES
Information EOMES
- Description
This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
- Full Name
eomesodermin
- Source NCBI
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 41,346
- Non-redundant peaks
- 41,346
TF Classification
- Super Class
- Immunoglobulin fold
- Class
- T-Box factors
- Familly
- TBrain-related factors
- Sub Familly
- None
Source TFClass
External IDs
- JASPAR
- MA0800
- Ensembl
- ENSG00000163508
- UniProt
- O95936
- Genevisible
- O95936
- RefSeq
- NM_001278182
- Aliases
- TBR2