CREM
Information CREM
- Description
This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]
- Full Name
cAMP responsive element modulator
- Source NCBI
ReMap Statistics
- Datasets
- 3
- Biotypes
- 3
- Peaks
- 139,194
- Non-redundant peaks
- 112,974
TF Classification
- Super Class
- Basic domains
- Class
- Basic leucine zipper factors (bZIP)
- Familly
- CREB-related factors
- Sub Familly
- CREB-like factors
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000095794
- UniProt
- Q03060
- Genevisible
- Q03060
- RefSeq
- NM_001267562
- Aliases
- CREM-2; ICER; hCREM-2
Datasets Table for CREM
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| CREM | GM12878 | ENCODE | Homo sapiens | ENCSR839XZU | 46,157 | |||
| CREM | Hep-G2 | ENCODE | Homo sapiens | ENCSR903ELW | 27,359 | |||
| CREM | K-562 | ENCODE | Homo sapiens | ENCSR077DKV | 65,678 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |