CDK9
Information CDK9
- Description
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]
- Full Name
cyclin dependent kinase 9
- Source NCBI
ReMap Statistics
- Datasets
- 25
- Biotypes
- 9
- Peaks
- 329,568
- Non-redundant peaks
- 161,351
TF Classification
- Super Class
- Unknown
- Class
- Unknown
- Familly
- Unknown
- Sub Familly
- Unknown
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000136807
- UniProt
- P50750
- Genevisible
- P50750
- RefSeq
- NM_001261
- Aliases
- C-2k; CDC2L4; CTK1; PITALRE; TAK
Datasets Table for CDK9
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| CDK9 | BT-474 | ENA | Homo sapiens | ERP010664 | 5,615 | |||
| CDK9 | BT-474 | INHHDAC | ENA | Homo sapiens | ERP010664 | 5,643 | ||
| CDK9 | CD4 | TH1_BAY | GEO | Homo sapiens | GSE62482 | 127 | ||
| CDK9 | CD4 | TH1_DMSO | GEO | Homo sapiens | GSE62482 | 158 | ||
| CDK9 | HEK293T | SIBRD4 | GEO | Homo sapiens | GSE51633 | 7,697 | ||
| CDK9 | HEK293T | SICTR | GEO | Homo sapiens | GSE51633 | 15,608 | ||
| CDK9 | HEK293T | SIJMJD6 | GEO | Homo sapiens | GSE51633 | 2,556 | ||
| CDK9 | A-375 | A771726 | GEO | Homo sapiens | GSE57431 | 4,762 | ||
| CDK9 | A-375 | DMSO | GEO | Homo sapiens | GSE57431 | 10,041 | ||
| CDK9 | A-375 | A771726 | GEO | Homo sapiens | GSE68052 | 4,170 | ||
| CDK9 | A-375 | DMSO | GEO | Homo sapiens | GSE68052 | 7,104 | ||
| CDK9 | MOLT-4 | DMSO | GEO | Homo sapiens | GSE79288 | 21,975 | ||
| CDK9 | MOLT-4 | JQ1 | GEO | Homo sapiens | GSE79288 | 19,263 | ||
| CDK9 | MV4-11 | DMSO | GEO | Homo sapiens | GSE82116 | 36,719 | ||
| CDK9 | P493-6 | GEO | Homo sapiens | GSE36354 | 7,633 | |||
| CDK9 | P493-6 | CMYC_1H | GEO | Homo sapiens | GSE36354 | 1,444 | ||
| CDK9 | P493-6 | CMYC_24H | GEO | Homo sapiens | GSE36354 | 255 | ||
| CDK9 | MM1-S | DMSO | GEO | Homo sapiens | GSE42161 | 35,623 | ||
| CDK9 | MM1-S | JQ1 | GEO | Homo sapiens | GSE42161 | 116 | ||
| CDK9 | MM1-S | DMSO | GEO | Homo sapiens | GSE42355 | 6,940 | ||
| CDK9 | MM1-S | JQ1_500NM | GEO | Homo sapiens | GSE42355 | 42,847 | ||
| CDK9 | MM1-S | JQ1_5000NM | GEO | Homo sapiens | GSE49224 | 34,873 | ||
| CDK9 | MM1-S | JQ1_50NM | GEO | Homo sapiens | GSE49224 | 28,650 | ||
| CDK9 | HCT-116 | SHCTR | GEO | Homo sapiens | GSE70408 | 120 | ||
| CDK9 | HCT-116 | GEO | Homo sapiens | GSE72622 | 29,629 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |