BRD4

Information BRD4

Description

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

Full Name

bromodomain containing 4

Source NCBI

ReMap Statistics

Datasets
174
Biotypes
65
Peaks
5,667,803
Non-redundant peaks
1,029,004

TF Classification

Super Class
Unknown
Class
Unknown
Familly
Unknown
Sub Familly
Unknown

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000141867
UniProt
O60885
Genevisible
O60885
RefSeq
NM_001330384
Aliases
CAP; HUNK1; HUNKI; MCAP

External links
All peaks BRD4
Download BED file
Non redundant peaks BRD4
Download BED file
SEQUENCES BRD4
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for BRD4

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
BRD4 BT-474 ENA Homo sapiens ERP010664 6,490
BRD4 BT-474 INHHDAC ENA Homo sapiens ERP010664 3,809
BRD4 BCBL-1 TREx-F3H3-K-Rt GEO Homo sapiens GSE103395 592
BRD4 Hep-G2 ENCODE Homo sapiens ENCSR514EOE 7,292
BRD4 K-562 ENCODE Homo sapiens ENCSR583ACG 9,288
BRD4 MCF-10A ENA Homo sapiens ERP003925 38,485
BRD4 MDA-MB-157 ENA Homo sapiens ERP003925 21,240
BRD4 MDA-MB-231 ENA Homo sapiens ERP003925 7,002
BRD4 NCI-H2171 GEO Homo sapiens GSE101821 5,639
BRD4 T-47D ENA Homo sapiens ERP003925 21,603
BRD4 MV4-11-B BI00894999_100nM_4h GEO Homo sapiens GSE101821 64,851
BRD4 MV4-11-B BI00894999_1nM_4h GEO Homo sapiens GSE101821 82,832
BRD4 MV4-11-B BI00894999_35nM_4h GEO Homo sapiens GSE101821 68,421
BRD4 MV4-11-B DMSO GEO Homo sapiens GSE101821 49,432
BRD4 LNAR Enz GEO Homo sapiens GSE103449 493
BRD4 LREX GEO Homo sapiens GSE103449 168
BRD4 OCI-AML3 GEO Homo sapiens GSE104745 16,475
BRD4 OCI-AML3 JQ1_500nM_24h GEO Homo sapiens GSE104745 1,557
BRD4 BE2C GEO Homo sapiens GSE80151 20,935
BRD4 CD4 GEO Homo sapiens GSE33281 88,615
BRD4 CD4 JG1 GEO Homo sapiens GSE33281 72,298
BRD4 CD4 TH1_BAY GEO Homo sapiens GSE62482 19,341
BRD4 CD4 TH1_DMSO GEO Homo sapiens GSE62482 35,557
BRD4 DND41 GEO Homo sapiens GSE54379 10,961
BRD4 DND41 E GEO Homo sapiens GSE54379 23,953
BRD4 HCC1395 GEO Homo sapiens GSE63581 65,899
BRD4 HCC1395 JQ1 GEO Homo sapiens GSE63581 30,139
BRD4 HCT15 GEO Homo sapiens GSE73319 33,224
BRD4 HEK293T GEO Homo sapiens GSE39579 14,073
BRD4 HEK293T GEO Homo sapiens GSE50491 46
BRD4 HEK293T GEO Homo sapiens GSE51633 26,688
BRD4 HeLa GEO Homo sapiens GSE51633 17,143
BRD4 hESC GEO Homo sapiens GSE33281 63,822
BRD4 HFOB DIFF GEO Homo sapiens GSE82295 18,667
BRD4 HT29 GEO Homo sapiens GSE73319 28,261
BRD4 Jurkat GEO Homo sapiens GSE83777 47,877
BRD4 KOPTK1 GEO Homo sapiens GSE54379 39,100
BRD4 KOPTK1 E GEO Homo sapiens GSE54379 37,789
BRD4 LP1 GEO Homo sapiens GSE71909 1,247
BRD4 LP1 CPI203 GEO Homo sapiens GSE71909 181
BRD4 LP1 SGCCBP300 GEO Homo sapiens GSE71909 651
BRD4 MPNST DMSO GEO Homo sapiens GSE62499 95,431
BRD4 MPNST PDJQ GEO Homo sapiens GSE62499 45,258
BRD4 SEM GEO Homo sapiens GSE83671 34,432
BRD4 SGBS GEO Homo sapiens GSE64233 6,101
BRD4 SGBS TNF GEO Homo sapiens GSE64233 8,194
BRD4 SUM1315 DMSO GEO Homo sapiens GSE63581 26,930
BRD4 SUM149 DMSO GEO Homo sapiens GSE63581 14,110
BRD4 SUM159 GEO Homo sapiens GSE63581 623
BRD4 SUM159 RES GEO Homo sapiens GSE63581 1,935
BRD4 SUM185 DMSO GEO Homo sapiens GSE63581 16,399
BRD4 SW480 GEO Homo sapiens GSE110473 39,008
BRD4 SW480 16h_TNF-a GEO Homo sapiens GSE110473 34,110
BRD4 SW480 GEO Homo sapiens GSE73319 25,012
BRD4 HCC1806 100nMtrametinib_24h GEO Homo sapiens GSE87418 30,891
BRD4 HCC1806 100nMtrametinib300nMJQ1_24h GEO Homo sapiens GSE87418 19,741
BRD4 HCC1806 300nMJQ1_24h GEO Homo sapiens GSE87418 12,839
BRD4 HCC1806 DMSO_24h GEO Homo sapiens GSE87418 17,101
BRD4 HUVEC-C GEO Homo sapiens GSE53998 21,185
BRD4 HUVEC-C TNF GEO Homo sapiens GSE53998 22,776
BRD4 HUVEC-C TNF_JQ1 GEO Homo sapiens GSE53998 6,308
BRD4 HUVEC-C GEO Homo sapiens GSE60171 4,085
BRD4 HUVEC-C MS417 GEO Homo sapiens GSE60171 84
BRD4 HUVEC-C modETS1 GEO Homo sapiens GSE93030 16,570
BRD4 HUVEC-C modGFP GEO Homo sapiens GSE93030 13,609
BRD4 IMR-90 PROLIF GEO Homo sapiens GSE74238 621
BRD4 IMR-90 QUIES GEO Homo sapiens GSE74238 73,760
BRD4 IMR-90 SENES GEO Homo sapiens GSE74238 27,037
BRD4 MCF-10A GEO Homo sapiens GSE72931 82,441
BRD4 MCF-7 GEO Homo sapiens GSE55921 10,180
BRD4 MCF-7 E2 GEO Homo sapiens GSE55921 9,678
BRD4 MDA-MB-436 DMSO GEO Homo sapiens GSE63581 6,192
BRD4 MOLM-14 CA25 GEO Homo sapiens GSE65138 26,007
BRD4 MOLM-14 DMSO GEO Homo sapiens GSE65138 41,965
BRD4 MOLM-14 IBET GEO Homo sapiens GSE65138 40,682
BRD4 MOLT-4 DMSO GEO Homo sapiens GSE79288 17,089
BRD4 Mutu-1 JQ1 GEO Homo sapiens GSE84213 9,066
BRD4 Mutu-1 vehicle GEO Homo sapiens GSE84213 30,292
BRD4 MV4-11 DMSO GEO Homo sapiens GSE71776 38,449
BRD4 MV4-11 IBET GEO Homo sapiens GSE71776 38,512
BRD4 MV4-11 IBET_SGC GEO Homo sapiens GSE71776 27,606
BRD4 MV4-11 SGC GEO Homo sapiens GSE71776 61,906
BRD4 NCI-H2171 GEO Homo sapiens GSE42355 91,761
BRD4 NCI-H2171 DMSO GEO Homo sapiens GSE49224 6,186
BRD4 NCI-H2171 JQ1 GEO Homo sapiens GSE49224 42
BRD4 OCI-Ly1 DMSO GEO Homo sapiens GSE53601 5,846
BRD4 OCI-Ly1 JQ1 GEO Homo sapiens GSE53601 13,561
BRD4 OVCAR-3 DMSO GEO Homo sapiens GSE77568 14,203
BRD4 OVCAR-3 JQ1 GEO Homo sapiens GSE77568 375
BRD4 P493-6 MYC_0H GEO Homo sapiens GSE42262 4,023
BRD4 P493-6 MYC_1H GEO Homo sapiens GSE42262 8,260
BRD4 P493-6 MYC_24H GEO Homo sapiens GSE42262 2,003
BRD4 RH4 GEO Homo sapiens GSE83726 16,567
BRD4 SUM159PT 100nMtrametinib_1h GEO Homo sapiens GSE87418 61,944
BRD4 SUM159PT 100nMtrametinib1uMSGCCBP30_24h GEO Homo sapiens GSE87418 87,444
BRD4 SUM159PT 100nMtrametinib_24h GEO Homo sapiens GSE87418 85,237
BRD4 SUM159PT 100nMtrametinib300nMJIB04_24h GEO Homo sapiens GSE87418 96,580
BRD4 SUM159PT 100nMtrametinib300nMJQ1_24h GEO Homo sapiens GSE87418 37,418
BRD4 SUM159PT 100nMtrametinib30nMbortezomib_8h GEO Homo sapiens GSE87418 83,542
BRD4 SUM159PT 100nMtrametinib_48h GEO Homo sapiens GSE87418 84,845
BRD4 SUM159PT 100nMtrametinib_4h GEO Homo sapiens GSE87418 56,375
BRD4 SUM159PT 100nMtrametinib_72h GEO Homo sapiens GSE87418 78,003
BRD4 SUM159PT 100nMtrametinib_8h GEO Homo sapiens GSE87418 64,081
BRD4 SUM159PT 300nMJQ1_24h GEO Homo sapiens GSE87418 23,791
BRD4 SUM159PT 30nMbortezomib_8h GEO Homo sapiens GSE87418 81,674
BRD4 SUM159PT DMSO_24h GEO Homo sapiens GSE87418 58,621
BRD4 SUM159PT DMSO_48h GEO Homo sapiens GSE87418 52,429
BRD4 SUM159PT DMSO_72h GEO Homo sapiens GSE87418 38,067
BRD4 SUM159PT DMSO_8h GEO Homo sapiens GSE87418 59,138
BRD4 SUM159PT Dox_48h GEO Homo sapiens GSE87418 55,813
BRD4 SUM159PT shMYC_BRD4_100nMtrametinib_48h GEO Homo sapiens GSE87418 93,297
BRD4 SUM159PT shMYC_DMSO_48h GEO Homo sapiens GSE87418 58,667
BRD4 SUM159PT shMYC_dox_48h GEO Homo sapiens GSE87418 72,660
BRD4 SUM229PE neg_30nMtrametinib_24h GEO Homo sapiens GSE87418 34,743
BRD4 SUM229PE neg_DMSO_24h GEO Homo sapiens GSE87418 27,764
BRD4 SUM229PE pos_30nMtrametinib_24h GEO Homo sapiens GSE87418 21,232
BRD4 SUM229PE pos_DMSO_24h GEO Homo sapiens GSE87418 29,759
BRD4 T-47D DMSO GEO Homo sapiens GSE63581 26,136
BRD4 CLL patient1 GEO Homo sapiens GSE109411 37,225
BRD4 CLL patient1_4h_CpG GEO Homo sapiens GSE109411 35,502
BRD4 CLL patient1_4h_CpG_BET GEO Homo sapiens GSE109411 19,348
BRD4 CLL patient2 GEO Homo sapiens GSE109411 55,888
BRD4 CLL patient2_4h_CpG GEO Homo sapiens GSE109411 30,078
BRD4 CLL patient2_4h_CpG_BET GEO Homo sapiens GSE109411 36,089
BRD4 CLL patient3 GEO Homo sapiens GSE109411 39,129
BRD4 CLL patient3_4h_CpG GEO Homo sapiens GSE109411 47,912
BRD4 CLL patient3_4h_CpG_BET GEO Homo sapiens GSE109411 24,527
BRD4 CLL patient4 GEO Homo sapiens GSE109411 38,394
BRD4 CLL patient4_4h_CpG GEO Homo sapiens GSE109411 33,418
BRD4 CLL patient4_4h_CpG_BET GEO Homo sapiens GSE109411 21,630
BRD4 MM1-S DMSO GEO Homo sapiens GSE42161 26,518
BRD4 MM1-S JQ1 GEO Homo sapiens GSE42161 690
BRD4 MM1-S JQ1_500NM GEO Homo sapiens GSE42355 41,681
BRD4 MM1-S JQ1_50NM GEO Homo sapiens GSE42355 50,254
BRD4 MM1-S JQ1_5NM GEO Homo sapiens GSE42355 57,587
BRD4 MM1-S JQ1_5UM GEO Homo sapiens GSE42355 36,962
BRD4 U-87MG GEO Homo sapiens GSE42355 83,853
BRD4 MM1-S GEO Homo sapiens GSE43743 46,579
BRD4 MM1-S GEO Homo sapiens GSE45984 26,523
BRD4 MM1-S JQ1_150NM GEO Homo sapiens GSE49224 42,778
BRD4 U-87MG DMSO GEO Homo sapiens GSE49224 106,168
BRD4 U-87MG JQ1 GEO Homo sapiens GSE49224 109,501
BRD4 HCT-116 GEO Homo sapiens GSE57628 12,886
BRD4 HCT-116 JQ1 GEO Homo sapiens GSE57628 3,018
BRD4 COLO-205 GEO Homo sapiens GSE73319 30,284
BRD4 COLO-320 GEO Homo sapiens GSE73319 9,327
BRD4 COLO-741 GEO Homo sapiens GSE73319 57,154
BRD4 HCT-116 GEO Homo sapiens GSE73319 7,073
BRD4 GEN2-2 GEO Homo sapiens GSE76147 340
BRD4 SK-N-BE2-C GEO Homo sapiens GSE80151 21,438
BRD4 Hs-352-Sk GEO Homo sapiens GSE83725 4,326
BRD4 Hs-352-Sk PAX3-FOXO1-vector GEO Homo sapiens GSE83725 14,616
BRD4 retina AB1-FW13 GEO Homo sapiens GSE86981 12,888
BRD4 retina AB1-FW15 GEO Homo sapiens GSE86981 83,875
BRD4 retina AB1-FW20 GEO Homo sapiens GSE86981 31,402
BRD4 retina AB1-FW23 GEO Homo sapiens GSE86981 33,473
BRD4 retina AB1-RB GEO Homo sapiens GSE86981 74,266
BRD4 LNCaP-C4-2 EV GEO Homo sapiens GSE88871 5,943
BRD4 LNCaP-C4-2 EV_JQ1 GEO Homo sapiens GSE88871 342
BRD4 LNCaP-C4-2 F133V GEO Homo sapiens GSE88871 80,615
BRD4 LNCaP-C4-2 F133V_JQ1 GEO Homo sapiens GSE88871 45,419
BRD4 LNCaP-C4-2 OE GEO Homo sapiens GSE88871 72,010
BRD4 CHL-1 GEO Homo sapiens GSE95585 34,992
BRD4 CHL-1 BAY123897 GEO Homo sapiens GSE95585 7,592
BRD4 CHL-1 OTX015 GEO Homo sapiens GSE95585 5,855
BRD4 GM15850 DMSO GEO Homo sapiens GSE99402 27,908
BRD4 GM15850 PA1_JQ1 GEO Homo sapiens GSE99402 17,908
BRD4 GM15850 Syn-TEF1 GEO Homo sapiens GSE99402 30,667
BRD4 K-562 DMSO GEO Homo sapiens GSE99178 34,572
BRD4 K-562 JQ1_2h GEO Homo sapiens GSE99178 21,844
BRD4 K-562 JQ1_6h GEO Homo sapiens GSE99178 15,045
BRD4 KK-1 DMSO GEO Homo sapiens GSE94732 5,164
BRD4 KK-1 JQ1 GEO Homo sapiens GSE94732 3,288
BRD4 NMC24335 GEO Homo sapiens GSE96775 25,601
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.