BCL11A

Information BCL11A

Description

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Full Name

BAF chromatin remodeling complex subunit BCL11A

Source NCBI

ReMap Statistics

Datasets
28
Biotypes
9
Peaks
1,086,053
Non-redundant peaks
365,497

TF Classification

Super Class
Zinc-coordinating DNA-binding domains
Class
C2H2 zinc finger factors
Familly
Factors with multiple dispersed zinc fingers
Sub Familly
BCL11

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000119866
UniProt
Q9H165
Genevisible
Q9H165
RefSeq
NM_001363864
Aliases
BCL11A-L; BCL11A-S; BCL11A-XL; CTIP1; HBFQTL5; ZNF856
All peaks BCL11A
Download BED file
Non redundant peaks BCL11A
Download BED file
SEQUENCES BCL11A
Download FASTA file
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Datasets Table for BCL11A

Target nameTarget modificationEcotype/StrainBiotypeBiotype modificationSourceSpeciesExperimentPeaks
BCL11A CD34 Day3_30min GEO Homo sapiens GSE104676 53,395
BCL11A CD34 Day3_60min GEO Homo sapiens GSE104676 112,171
BCL11A CD34 Day3_90min GEO Homo sapiens GSE104676 123,652
BCL11A CD34 Day5_30min GEO Homo sapiens GSE104676 50,640
BCL11A CD34 Day5_60min GEO Homo sapiens GSE104676 93,530
BCL11A CD34 Day5_90min GEO Homo sapiens GSE104676 137,826
BCL11A CD34 Day7_15min GEO Homo sapiens GSE104676 5,439
BCL11A CD34 Day7_30min GEO Homo sapiens GSE104676 19,284
BCL11A CD34 Day7_60min GEO Homo sapiens GSE104676 17,305
BCL11A CD34 Day7_90min GEO Homo sapiens GSE104676 18,644
Target nameTarget modificationEcotype/StrainBiotypeBiotype modificationSourceSpeciesExperimentPeaks
Showing 1 to 10 of 28 entries

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

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The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.