|T. Regulators ChIP-seq
|Datasets (QC pass)
Thaliana Transcriptional Regulators
Transcriptional factors regions
Thaliana Histone modifications
Histone binding regions
Finally we also applied our pipeline to all available histone ChIP-seq data and identifed 4.5 million broad and gapped peaks.
In short, libraries are constructed using native genomic DNA, which are incubated with an affinity-tagged in vitro expressed TF, and TF-DNA complexes are purified using magnetic separation of the affinity tag.
A link to the Ensembl Genome Browser was also added to facilitate genomic integration of the binding sites with other genome annotations. Our BED tracks allow for the visualization of our catalogues of binding sites on the human genome. Finally, different analyses such as the quality of datasets and DNA constraint analysis are provided for each transcription factor.
The ReMap BED files are available to download either for a given transcriptional regulator, by Biotype or for the entire catalog as one very large BED file.
For Homo sapiens the GRCh38/hg38 assembly is currently the supported assembly, but our files can be lifted to hg19 with liftover. We also provide an archive of the ReMap 2018 and 2015 catalogs.
For Arabidopsis thaliana we provide BED files for transcriptional regulators, histones marks, ecotypes and biotype coupled with a given ecotype. The TAIR10 assembly is the only assembly supported by ReMap.