ZEB2
Information ZEB2
- Description
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]
- Full Name
zinc finger E-box binding homeobox 2
- Source NCBI
ReMap Statistics
- Datasets
- 4
- Biotypes
- 3
- Peaks
- 141,120
- Non-redundant peaks
- 104,732
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Homeo domain factors
- Familly
- HD-ZF factors
- Sub Familly
- ZEB
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000169554
- UniProt
- O60315
- Genevisible
- O60315
- RefSeq
- NM_001171653
- Aliases
- HSPC082; KIAA0569; SIP-1; SIP1; SMADIP1; ZFHX1B
Datasets Table for ZEB2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| ZEB2 | HEK293 | ENCODE | Homo sapiens | ENCSR417VWF | 61,847 | |||
| ZEB2 | liver | GEO | Homo sapiens | GSE103048 | 709 | |||
| ZEB2 | K-562 | ENCODE | Homo sapiens | ENCSR004GKA | 43,242 | |||
| ZEB2 | K-562 | ENCODE | Homo sapiens | ENCSR322CFO | 35,322 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |