ZEB1
Information ZEB1
- Description
This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010]
- Full Name
zinc finger E-box binding homeobox 1
- Source NCBI
ReMap Statistics
- Datasets
- 10
- Biotypes
- 8
- Peaks
- 156,953
- Non-redundant peaks
- 110,797
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Homeo domain factors
- Familly
- HD-ZF factors
- Sub Familly
- ZEB
Source TFClass
External IDs
- JASPAR
- MA0103
- Ensembl
- ENSG00000148516
- UniProt
- P37275
- Genevisible
- P37275
- RefSeq
- NM_001128128
- Aliases
- AREB6; BZP; DELTAEF1; FECD6; NIL-2-A; NIL2A; PPCD3; TCF8; ZFHEP; ZFHX1A
Datasets Table for ZEB1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| ZEB1 | GM12878 | ENCODE | Homo sapiens | ENCSR000BND | 50,700 | |||
| ZEB1 | HEK293 | ENCODE | Homo sapiens | ENCSR909HMT | 22,309 | |||
| ZEB1 | Hep-G2 | ENCODE | Homo sapiens | ENCSR000BVN | 13,176 | |||
| ZEB1 | NCI-H1975 | GEO | Homo sapiens | GSE106896 | 4,068 | |||
| ZEB1 | NCI-H1975 | resistant | GEO | Homo sapiens | GSE106896 | 11,177 | ||
| ZEB1 | neuron | bipolar_doxy_4d | ENCODE | Homo sapiens | ENCSR418KUS | 19,957 | ||
| ZEB1 | PDAC | GEO | Homo sapiens | GSE64557 | 19,983 | |||
| ZEB1 | RKO | GEO | Homo sapiens | GSE88734 | 10,422 | |||
| ZEB1 | MIA-PaCa-2 | GEO | Homo sapiens | GSE88734 | 4,028 | |||
| ZEB1 | MIA-PaCa-2 | WT | GEO | Homo sapiens | GSE88734 | 1,133 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |