YBX1

Information YBX1

Description

This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]

Full Name

Y-box binding protein 1

Source NCBI

ReMap Statistics

Datasets
4
Biotypes
4
Peaks
10,705
Non-redundant peaks
8,438

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000065978
UniProt
P67809
Genevisible
P67809
RefSeq
NM_004559
Aliases
BP-8; CBF-A; CSDA2; CSDB; DBPB; EFI-A; MDR-NF1; NSEP-1; NSEP1; YB-1; YB1
All peaks YBX1
Download BED file
Non redundant peaks YBX1
Download BED file
SEQUENCES YBX1
Download FASTA file
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Datasets Table for YBX1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
YBX1 GM12878 ENCODE Homo sapiens ENCSR205SKQ 3,125
YBX1 Hep-G2 ENCODE Homo sapiens ENCSR799GOY 4,914
YBX1 K-562 ENCODE Homo sapiens ENCSR107RHZ 1,696
YBX1 MCF-7 ENCODE Homo sapiens ENCSR864KNH 970
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.