UBTF
Information UBTF
- Description
This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]
- Full Name
upstream binding transcription factor
- Source NCBI
ReMap Statistics
- Datasets
- 6
- Biotypes
- 4
- Peaks
- 57,398
- Non-redundant peaks
- 42,708
TF Classification
- Super Class
- Other all-alpha-helical DNA-binding domains
- Class
- High-mobility group (HMG) domain factors
- Familly
- UBF-related factors
- Sub Familly
- UBF-related factors
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000108312
- UniProt
- P17480
- Genevisible
- P17480
- RefSeq
- NM_001076683
- Aliases
- CONDBA; NOR-90; UBF; UBF-1; UBF1; UBF2
Datasets Table for UBTF
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| UBTF | GM12878 | ENCODE | Homo sapiens | ENCSR459FTB | 5,596 | |||
| UBTF | K-562 | ENCODE | Homo sapiens | ENCSR000EFW | 13,835 | |||
| UBTF | K-562 | ENCODE | Homo sapiens | ENCSR000EFZ | 37,036 | |||
| UBTF | HeLa-S3 | ENCODE | Homo sapiens | ENCSR634ZGP | 280 | |||
| UBTF | hESC | GEO | Homo sapiens | GSE76586 | 390 | |||
| UBTF | hESC | activinA | GEO | Homo sapiens | GSE76586 | 261 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |