TOP1
Information TOP1
- Description
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]
- Full Name
DNA topoisomerase I
- Source NCBI
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 14,008
- Non-redundant peaks
- 10,333
TF Classification
- Super Class
- Unknown
- Class
- Unknown
- Familly
- Unknown
- Sub Familly
- Unknown
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000198900
- UniProt
- P11387
- Genevisible
- P11387
- RefSeq
- NM_003286
- Aliases
- TOPI
Datasets Table for TOP1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| TOP1 | LNCaP | GEO | Homo sapiens | GSE63202 | 5,244 | |||
| TOP1 | LNCaP | DHT | GEO | Homo sapiens | GSE63202 | 8,584 | ||
| TOP1 | HCT-116 | JQ1 | GEO | Homo sapiens | GSE57628 | 180 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |