STAT1
Information STAT1
- Description
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Full Name
signal transducer and activator of transcription 1
- Source NCBI
ReMap Statistics
- Datasets
- 16
- Biotypes
- 7
- Peaks
- 347,162
- Non-redundant peaks
- 190,086
TF Classification
- Super Class
- Immunoglobulin fold
- Class
- STAT domain factors
- Familly
- STAT factors
- Sub Familly
- None
Source TFClass
External IDs
- JASPAR
- MA0517
- Ensembl
- ENSG00000115415
- UniProt
- P42224
- Genevisible
- P42224
- RefSeq
- NM_007315
- Aliases
- CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
Datasets Table for STAT1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| STAT1 | GM12878 | ENCODE | Homo sapiens | ENCSR000DZM | 1 | |||
| STAT1 | GM12878 | ENCODE | Homo sapiens | ENCSR332EYT | 5,377 | |||
| STAT1 | K-562 | ENCODE | Homo sapiens | ENCSR000EHJ | 2,435 | |||
| STAT1 | K-562 | ENCODE | Homo sapiens | ENCSR000EHK | 1,266 | |||
| STAT1 | K-562 | ENCODE | Homo sapiens | ENCSR000FAU | 871 | |||
| STAT1 | K-562 | ENCODE | Homo sapiens | ENCSR000FAV | 592 | |||
| STAT1 | pS727 | SET-2 | GEO | Homo sapiens | GSE100566 | 77,817 | ||
| STAT1 | SET-2 | cortistatin-A | GEO | Homo sapiens | GSE100566 | 13,398 | ||
| STAT1 | SET-2 | DMSO | GEO | Homo sapiens | GSE100566 | 25,458 | ||
| STAT1 | HeLa-S3 | ENCODE | Homo sapiens | ENCSR000EZK | 18,141 | |||
| STAT1 | AGS | GEO | Homo sapiens | GSE79707 | 1,450 | |||
| STAT1 | CD14 | GEO | Homo sapiens | GSE43036 | 10,636 | |||
| STAT1 | CD14 | INFG | GEO | Homo sapiens | GSE43036 | 57,679 | ||
| STAT1 | CD14 | INFG_LPS | GEO | Homo sapiens | GSE43036 | 67,375 | ||
| STAT1 | CD14 | LPS | GEO | Homo sapiens | GSE43036 | 49,126 | ||
| STAT1 | NCI-H358 | GEO | Homo sapiens | GSE79707 | 15,540 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |