SP140
Information SP140
- Description
This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
- Full Name
SP140 nuclear body protein
- Source NCBI
ReMap Statistics
- Datasets
- 2
- Biotypes
- 1
- Peaks
- 401,784
- Non-redundant peaks
- 297,583
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000079263
- UniProt
- Q13342
- Genevisible
- Q13342
- RefSeq
- NM_001005176
- Aliases
- LYSP100; LYSP100-A; LYSP100-B
Datasets Table for SP140
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SP140 | macrophage | GEO | Homo sapiens | GSE90126 | 154,461 | |||
| SP140 | macrophage | LPS | GEO | Homo sapiens | GSE90126 | 247,323 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |