SNAI2
Information SNAI2
- Description
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]
- Full Name
snail family transcriptional repressor 2
- Source NCBI
ReMap Statistics
- Datasets
- 6
- Biotypes
- 1
- Peaks
- 130,468
- Non-redundant peaks
- 86,242
TF Classification
- Super Class
- Zinc-coordinating DNA-binding domains
- Class
- C2H2 zinc finger factors
- Familly
- More than 3 adjacent zinc finger factors
- Sub Familly
- Snail-like factors
Source TFClass
External IDs
- JASPAR
- MA0745
- Ensembl
- ENSG00000019549
- UniProt
- O43623
- Genevisible
- O43623
- RefSeq
- NM_003068
- Aliases
- SLUG; SLUGH; SLUGH1; SNAIL2; WS2D
Datasets Table for SNAI2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SNAI2 | keratinocyte | LacZ | GEO | Homo sapiens | GSE55421 | 25,014 | ||
| SNAI2 | keratinocyte | LacZ_DIFF | GEO | Homo sapiens | GSE55421 | 4,424 | ||
| SNAI2 | keratinocyte | SHCTR | GEO | Homo sapiens | GSE55421 | 7,108 | ||
| SNAI2 | keratinocyte | SHSNAI2 | GEO | Homo sapiens | GSE55421 | 879 | ||
| SNAI2 | keratinocyte | SNAI2 | GEO | Homo sapiens | GSE55421 | 12,485 | ||
| SNAI2 | keratinocyte | SNAI2_diff | GEO | Homo sapiens | GSE55421 | 80,558 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |