SMARCA4

Information SMARCA4

Description

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Full Name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

Source NCBI

ReMap Statistics

Datasets
24
Biotypes
15
Peaks
564,162
Non-redundant peaks
380,894

TF Classification

Super Class
Unknown
Class
Unknown
Familly
Unknown
Sub Familly
Unknown

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000127616
UniProt
P51532
Genevisible
P51532
RefSeq
NM_001128844
Aliases
BAF190; BAF190A; BRG1; CSS4; FLJ39786; MRD16; RTPS2; SNF2; SNF2-BETA; SNF2L4; SNF2LB; SWI2; hSNF2b
All peaks SMARCA4
Download BED file
Non redundant peaks SMARCA4
Download BED file
SEQUENCES SMARCA4
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for SMARCA4

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
SMARCA4 WA09 GEO Homo sapiens GSE105028 1,792
SMARCA4 Aska-SS GEO Homo sapiens GSE108025 35,450
SMARCA4 Aska-SS shSSX GEO Homo sapiens GSE108025 47,237
SMARCA4 K-562 ENCODE Homo sapiens ENCSR587OQL 74,342
SMARCA4 K-562 ENCODE Homo sapiens ENCSR643VTW 61,980
SMARCA4 SYO-1 GEO Homo sapiens GSE108025 16,971
SMARCA4 HeLa-S3 ENCODE Homo sapiens ENCSR000EZC 5,175
SMARCA4 neuron bipolar_doxy_4d ENCODE Homo sapiens ENCSR839SFJ 109,209
SMARCA4 J-Lat GFP-Clone-A72_DMSO GEO Homo sapiens GSE100266 23,208
SMARCA4 J-Lat GFP-Clone-A72_JQ1 GEO Homo sapiens GSE100266 9,373
SMARCA4 501MEL SHCTR GEO Homo sapiens GSE61965 50,412
SMARCA4 501MEL SHMITF GEO Homo sapiens GSE61965 25,635
SMARCA4 501MEL SHSOX10 GEO Homo sapiens GSE61965 40,267
SMARCA4 BT-16 Dox GEO Homo sapiens GSE71504 18,444
SMARCA4 BT-16 NoDox GEO Homo sapiens GSE71504 1,430
SMARCA4 G-401 Dox GEO Homo sapiens GSE71504 918
SMARCA4 G-401 NoDox GEO Homo sapiens GSE71504 509
SMARCA4 MCF-10A GEO Homo sapiens GSE74716 27,092
SMARCA4 LNCaP r1881 GEO Homo sapiens GSE94682 11,962
SMARCA4 TTC-549 Dox GEO Homo sapiens GSE71504 6,701
SMARCA4 TTC-549 NoDox GEO Homo sapiens GSE71504 6,134
SMARCA4 HCT-116 GEO Homo sapiens GSE71510 1,883
SMARCA4 WA09 heat-shock GEO Homo sapiens GSE105028 3,058
SMARCA4 HS-SY-2 HA-tagged GEO Homo sapiens GSE108926 57,289
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.