SMAD5
Information SMAD5
- Description
The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
- Full Name
SMAD family member 5
- Source NCBI
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 50,051
- Non-redundant peaks
- 42,590
TF Classification
- Super Class
- beta-Hairpin exposed by an alpha/beta-scaffold
- Class
- SMAD/NF-1 DNA-binding domain factors
- Familly
- SMAD factors
- Sub Familly
- Regulatory Smads (R-Smad)
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000113658
- UniProt
- Q99717
- Genevisible
- Q99717
- RefSeq
- NM_001001419
- Aliases
- DWFC; Dwfc; JV5-1; MADH5
Datasets Table for SMAD5
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SMAD5 | GM12878 | ENCODE | Homo sapiens | ENCSR251OVJ | 15,450 | |||
| SMAD5 | K-562 | ENCODE | Homo sapiens | ENCSR000FCD | 34,601 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |