SKIL
Information SKIL
- Description
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Full Name
SKI like proto-oncogene
- Source NCBI
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 67,566
- Non-redundant peaks
- 63,529
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000136603
- UniProt
- P12757
- Genevisible
- P12757
- RefSeq
- NM_001145097
- Aliases
- SNO; SnoA; SnoI; SnoN
Datasets Table for SKIL
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SKIL | GM12878 | ENCODE | Homo sapiens | ENCSR212YKD | 48,361 | |||
| SKIL | K-562 | ENCODE | Homo sapiens | ENCSR336DXE | 19,205 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |