SIRT3
Information SIRT3
- Description
SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019]
- Full Name
sirtuin 3
- Source NCBI
ReMap Statistics
- Datasets
- 3
- Biotypes
- 1
- Peaks
- 58
- Non-redundant peaks
- 58
TF Classification
- Super Class
- Unknown
- Class
- Unknown
- Familly
- Unknown
- Sub Familly
- Unknown
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000142082
- UniProt
- Q9NTG7
- Genevisible
- Q9NTG7
- RefSeq
- NM_001017524
- Aliases
- SIR2L3
Datasets Table for SIRT3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SIRT3 | U2OS | GEO | Homo sapiens | GSE41000 | 55 | |||
| SIRT3 | U2OS | KOSIRT3 | GEO | Homo sapiens | GSE41000 | 1 | ||
| SIRT3 | U2OS | UV | GEO | Homo sapiens | GSE41000 | 2 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |