SETDB1
Information SETDB1
- Description
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]
- Full Name
SET domain bifurcated histone lysine methyltransferase 1
- Source NCBI
ReMap Statistics
- Datasets
- 7
- Biotypes
- 5
- Peaks
- 320,898
- Non-redundant peaks
- 251,997
TF Classification
- Super Class
- Unknown
- Class
- Unknown
- Familly
- Unknown
- Sub Familly
- Unknown
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000143379
- UniProt
- Q15047
- Genevisible
- Q15047
- RefSeq
- NM_001145415
- Aliases
- ESET; H3-K9-HMTase4; KG1T; KIAA0067; KMT1E; TDRD21
Datasets Table for SETDB1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| SETDB1 | HEK293 | ENCODE | Homo sapiens | ENCSR348AGV | 58,867 | |||
| SETDB1 | U2OS | ENCODE | Homo sapiens | ENCSR000EYD | 59,807 | |||
| SETDB1 | K-562 | ENCODE | Homo sapiens | ENCSR000AUT | 500 | |||
| SETDB1 | K-562 | ENCODE | Homo sapiens | ENCSR000EWD | 6,361 | |||
| SETDB1 | K-562 | ENCODE | Homo sapiens | ENCSR000EWI | 19,731 | |||
| SETDB1 | WN8532 | GEO | Homo sapiens | GSE36579 | 5,283 | |||
| SETDB1 | HeLa | MORC2-KO | GEO | Homo sapiens | GSE95456 | 170,349 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |