RXRA
Information RXRA
- Description
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
- Full Name
retinoid X receptor alpha
- Source NCBI
ReMap Statistics
- Datasets
- 8
- Biotypes
- 6
- Peaks
- 293,813
- Non-redundant peaks
- 168,027
TF Classification
- Super Class
- Zinc-coordinating DNA-binding domains
- Class
- Nuclear receptors with C4 zinc fingers
- Familly
- RXR-related receptors (NR2)
- Sub Familly
- Retinoid X receptors (NR2B)
Source TFClass
External IDs
- JASPAR
- MA1146
- Ensembl
- ENSG00000186350
- UniProt
- P19793
- Genevisible
- P19793
- RefSeq
- NM_001291920
- Aliases
- NR2B1
Datasets Table for RXRA
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| RXRA | GM12878 | ENCODE | Homo sapiens | ENCSR000BJD | 15,366 | |||
| RXRA | liver | ENCODE | Homo sapiens | ENCSR098XMN | 102,767 | |||
| RXRA | liver | ENCODE | Homo sapiens | ENCSR352QSB | 92,826 | |||
| RXRA | Hep-G2 | ENCODE | Homo sapiens | ENCSR000BHU | 29,254 | |||
| RXRA | JMSU-1 | GEO | Homo sapiens | GSE107734 | 15,403 | |||
| RXRA | JMSU-1 | RXRA-S427F | GEO | Homo sapiens | GSE107734 | 15,452 | ||
| RXRA | SK-N-SH | ENCODE | Homo sapiens | ENCSR000BVG | 17,980 | |||
| RXRA | WA01 | ENCODE | Homo sapiens | ENCSR000BJW | 4,765 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |