RUNX3
Information RUNX3
- Description
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
- Full Name
RUNX family transcription factor 3
- Source NCBI
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 114,798
- Non-redundant peaks
- 114,798
TF Classification
- Super Class
- Immunoglobulin fold
- Class
- Runt domain factors
- Familly
- Runt-related factors
- Sub Familly
- None
Source TFClass
External IDs
- JASPAR
- MA0684
- Ensembl
- ENSG00000020633
- UniProt
- Q13761
- Genevisible
- Q13761
- RefSeq
- NM_001031680
- Aliases
- AML2; CBFA3; PEBP2A3; PEBP2aC
Datasets Table for RUNX3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| RUNX3 | GM12878 | ENCODE | Homo sapiens | ENCSR000BRI | 114,798 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |