RUNX1
Information RUNX1
- Description
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Full Name
RUNX family transcription factor 1
- Source NCBI
ReMap Statistics
- Datasets
- 38
- Biotypes
- 24
- Peaks
- 1,204,330
- Non-redundant peaks
- 435,960
TF Classification
- Super Class
- Immunoglobulin fold
- Class
- Runt domain factors
- Familly
- Runt-related factors
- Sub Familly
- None
Source TFClass
External IDs
- JASPAR
- MA0002
- Ensembl
- ENSG00000159216
- UniProt
- Q01196
- Genevisible
- Q01196
- RefSeq
- NM_001001890
- Aliases
- AML1; AML1-EVI-1; AMLCR1; CBF2alpha; CBFA2; EVI-1; PEBP2A2; PEBP2aB; PEBP2alpha
Datasets Table for RUNX1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| RUNX1 | ALL-SIL | GEO | Homo sapiens | GSE102209 | 12,930 | |||
| RUNX1 | HL-60 | ENA | Homo sapiens | ERP008568 | 42 | |||
| RUNX1 | HL-60 | GEO | Homo sapiens | GSE107553 | 10,001 | |||
| RUNX1 | K-562 | ENCODE | Homo sapiens | ENCSR414TYY | 3,367 | |||
| RUNX1 | K-562 | ENCODE | Homo sapiens | ENCSR588AKU | 13,882 | |||
| RUNX1 | ME-1 | Human-leukemia_AI-10-49 | GEO | Homo sapiens | GSE101789 | 10,229 | ||
| RUNX1 | epididymis | HEE | GEO | Homo sapiens | GSE109061 | 56,788 | ||
| RUNX1 | epididymis | HEE_R1881 | GEO | Homo sapiens | GSE109061 | 2,655 | ||
| RUNX1 | AMLBLAST | GEO | Homo sapiens | GSE60130 | 47,132 | |||
| RUNX1 | BONE | MARROW | GEO | Homo sapiens | GSE64862 | 87,475 | ||
| RUNX1 | CD34 | GEO | Homo sapiens | GSE64862 | 47,141 | |||
| RUNX1 | CD34 | ADULT | GEO | Homo sapiens | GSE70660 | 13,533 | ||
| RUNX1 | CD34 | FETAL | GEO | Homo sapiens | GSE70660 | 6,292 | ||
| RUNX1 | HEK293T | GEO | Homo sapiens | GSE85524 | 110,682 | |||
| RUNX1 | Jurkat | GEO | Homo sapiens | GSE29180 | 10,041 | |||
| RUNX1 | Jurkat | GEO | Homo sapiens | GSE42575 | 5,020 | |||
| RUNX1 | Jurkat | GEO | Homo sapiens | GSE68976 | 35,003 | |||
| RUNX1 | Jurkat | GEO | Homo sapiens | GSE76181 | 44,066 | |||
| RUNX1 | Jurkat | GEO | Homo sapiens | GSE85524 | 39,533 | |||
| RUNX1 | NB4 | GEO | Homo sapiens | GSE81992 | 63,257 | |||
| RUNX1 | PBMC | GEO | Homo sapiens | GSE85524 | 103 | |||
| RUNX1 | SKNO1 | GEO | Homo sapiens | GSE23730 | 54,718 | |||
| RUNX1 | VCaP | DHT24H | GEO | Homo sapiens | GSE58428 | 61,063 | ||
| RUNX1 | CCRF-CEM | GEO | Homo sapiens | GSE33850 | 620 | |||
| RUNX1 | Kasumi-1 | GEO | Homo sapiens | GSE45738 | 25,195 | |||
| RUNX1 | Kasumi-1 | GEO | Homo sapiens | GSE62847 | 21,154 | |||
| RUNX1 | Kasumi-1 | GEO | Homo sapiens | GSE65427 | 17,323 | |||
| RUNX1 | MCF-7 | GEO | Homo sapiens | GSE75070 | 181 | |||
| RUNX1 | MV4-11 | GEO | Homo sapiens | GSE79899 | 53,564 | |||
| RUNX1 | NALM-6 | GEO | Homo sapiens | GSE109377 | 3,652 | |||
| RUNX1 | SKH1 | GEO | Homo sapiens | GSE87283 | 37,554 | |||
| RUNX1 | SKH1 | 10d | GEO | Homo sapiens | GSE87283 | 48,651 | ||
| RUNX1 | SKH1 | RUNX1-EVI1_KD | GEO | Homo sapiens | GSE87283 | 53,369 | ||
| RUNX1 | THP-1 | GEO | Homo sapiens | GSE79899 | 37,528 | |||
| RUNX1 | TSU-1621MT | GEO | Homo sapiens | GSE60477 | 86,170 | |||
| RUNX1 | U-937 | GEO | Homo sapiens | GSE65427 | 9,411 | |||
| RUNX1 | BCP-ALL | patient1 | GEO | Homo sapiens | GSE109377 | 40,144 | ||
| RUNX1 | ME-1 | GEO | Homo sapiens | GSE46044 | 34,861 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |